PROCESS FOR THE PRODUCTION OF EXTENDED-RELEASE PELLETS BY MELT SPRAYING IN A FLUIDIZED-BED DEVICE WITH ROTOR.

摘要

The present invention relates to a pellet production process by melt spraying, which allows the modification of the release rate of a pharmaceutically active substance between immediate and extended release, wherein the pellets comprise at least one pharmaceutically active substance, a hydroxypropylmethyl-cellulose, a polyoxylglyceride and carnauba wax