发明名称 |
PROCESS FOR PREPARING SULFONAMIDO-BENZOFURAN DERIVATIVES |
摘要 |
The invention relates to a process for preparing 5-sulfonamido-benzofuran derivatives of general formula: formula (I) in which R represents an alkyl or aryl group and R1 and R2 represent hydrogen or an alkyl or aryl group. According to the invention, the compounds of formula I are prepared by coupling a benzofuran derivative of general formula II, where X represents chlorine, bromine or iodine or a sulfonate group: formula (II) with a sulfonamide derivative of formula R-SO2-NH2, in the presence of a basic agent and of a catalyst system formed from a complex between a palladium compound and a ligand. |
申请公布号 |
WO2011124827(A1) |
申请公布日期 |
2011.10.13 |
申请号 |
WO2011FR50707 |
申请日期 |
2011.03.30 |
申请人 |
SANOFI-AVENTIS;PRIEM, THOMAS;VAYRON, PHILIPPE, PAUL |
发明人 |
PRIEM, THOMAS;VAYRON, PHILIPPE, PAUL |
分类号 |
C07D307/79;C07B45/04 |
主分类号 |
C07D307/79 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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