摘要 |
<p>The invention provides a liquid rotavirus immunogenic composition suitable for oral administration to a human infant, comprising a rotavirus antigen, a sugar and a carboxylate wherein said formulation has a pH of between about pH 5.0 and about pH 8.0 and comprises less than 1 mM phosphate, wherein said carboxylate is derived from a di-carboxylic acid with an average pK a > 4.</p> |