发明名称 Polymorphic form of 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-dihydro-1h-pyrrolizin-5-ylacetic acid
摘要 The present invention relates to a new crystalline modification of 6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,S-dihydro-1H-pyrrolizin-S-ylacetic acid which is referred to as polymorph B. It has a peak in the solid state 13C-NMR spectrum (with adamantane as external reference standard; CH group d=29.45 ppm) in the range from 179.8 to 180.2 ppm and can be processed directly to a pharmaceutical formulation.
申请公布号 US8034837(B2) 申请公布日期 2011.10.11
申请号 US20060886933 申请日期 2006.03.20
申请人 MERCKLE GMBH 发明人 ALBRECHT WOLFGANG;KAMMERMEIER THOMAS;STRIEGEL HANS-GUNTER;MERCKLE PHILIPP;LAUFER STEFAN
分类号 A61K31/407;C07D209/52 主分类号 A61K31/407
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