发明名称 |
Expression control elements from the Lemnaceae family |
摘要 |
Compositions and methods for regulating expression of nucleotide sequences of interest in a plant are provided. Compositions include novel nucleic acid molecules, and variants and fragments thereof, for expression control elements isolated from the Lemnaceae ubiquitin, r-histone and chitinase genes. A method for expressing a nucleotide sequence of interest in a plant using the expression control elements disclosed herein is further provided. The method includes introducing into a plant or plant cell or nodule an expression construct comprising an expression control element of the present invention operably linked to a nucleotide sequence of interest. In particular, the compositions and methods find use in enhancing expression of nucleotide sequences of interest in duckweed. Also provided is a novel Lemnaceae signal peptide-encoding sequence and the signal peptide encoded thereby. Where an expression construct of the invention is designed to express a polypeptide of interest, this novel signal peptide-encoding sequence can be included within the expression construct of the invention to provide for extracellular secretion of the encoded polypeptide of interest.
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申请公布号 |
US8034916(B2) |
申请公布日期 |
2011.10.11 |
申请号 |
US20090581752 |
申请日期 |
2009.10.19 |
申请人 |
BIOLEX THERAPEUTICS, INC. |
发明人 |
DICKEY LYNN F.;COX KEVIN M.;PEELE CHARLES G. |
分类号 |
C07H21/04;A01H5/00;C12N15/05;C12N15/82 |
主分类号 |
C07H21/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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