| 发明名称 |
RNAi modulation of MLL-AF4 and uses thereof |
| 摘要 |
The invention relates to compositions and methods for modulating the expression of the MLL-AF4 fusion gene, and more particularly to the downregulation of MLL-AF4 by chemically modified oligonucleotides.
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| 申请公布号 |
US8034793(B2) |
申请公布日期 |
2011.10.11 |
| 申请号 |
US20100700493 |
申请日期 |
2010.02.04 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
HEIDENREICH OLAF;VORNLOCHER HANS-PETER;HADWIGER PHILIPP |
| 分类号 |
A01N43/04;A61K31/70;C12N15/113 |
主分类号 |
A01N43/04 |
| 代理机构 |
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| 地址 |
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