METHOD OF PREPARING CERAMIC/POLYMER COMPOSITE SCAFFOLDS WITH BIOACTIVE MOLECULES FOR HARD TISSUE REGENERATION

摘要

The present invention relates to a new organic/inorganic composite scaffold containing bioactive molecules and a ceramic/polymer composite scaffold having one or multiple bioactive molecules and a method for preparing the same. The main architecture of the novel composite scaffold is composed of an inorganic ceramic scaffold with one or a plurality of hole(s) in which a biocompatible and biogradable polymer containing bioactive materials is incorporated. Since the organic/inorganic composite scaffold containing bioactive molecules according to the present invention is made of a ceramic as the main frame, it can utilize its mechanical property essential for in vivo adaption and superior bioactivity. In addition, the present invention can release bioactive molecules from a biogradable polymer incorporated in the hole in the ceramic. Thus, the present invention can maximize bioaffinity and response whereby it can be useful in tissue regeneration and drug delivery.