发明名称 NEUTRALIZING ANTIBODIES AGAINST GDF-8 AND USES THEREFOR
摘要 The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), in particular human antibodies, and antibody fragments, including those that inhibit GDF-8 activity in vitro and/or in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle or bone, or disorders of insulin metabolism.
申请公布号 US2011243953(A1) 申请公布日期 2011.10.06
申请号 US20090632383 申请日期 2009.12.07
申请人 WYETH;MEDLMMUNE LIMITED 发明人 VELDMAN GEERTRUIDA M.;DAVIES MONIQUE V.;SONG KENING;WOLFMAN NEIL M.;BRIDGES KRISTIE GROVE;FIELD ANNE;RUSSELL CAROLINE;VALGE-ARCHER VIIA
分类号 A61K39/395;A61P3/00;A61P3/04;A61P3/10;A61P11/00;A61P19/08;A61P21/00;C07H21/04;C07K16/00;C07K16/22;C12N1/00;C12N5/10;C12N15/13;C12N15/63;C12N15/70;C12P21/02 主分类号 A61K39/395
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