发明名称 |
CHIMERIC AND HUMANISED MONOCLONAL ANTIBODIES AGAINST INTERLEUKIN-13 |
摘要 |
The present invention concerns immunoglobulins, particularly antibodies which specifically bind human Interleukin 13 (hIL-13). Antibodies of the invention may be used in the treatment of a variety of diseases or disorders responsive to modulation of the interaction between hIL-13 and the human IL-13 receptor. Such diseases include severe asthma, atopic dermatitis, COPD and various fibrotic diseases. Pharmaceutical compositions comprising said antibodies and methods of manufacture are also disclosed.
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申请公布号 |
US2011243928(A1) |
申请公布日期 |
2011.10.06 |
申请号 |
US20100862235 |
申请日期 |
2010.08.24 |
申请人 |
ASHMAN CLAIRE;CASSIDY MARTIN JOHN;ELLIS JONATHAN HENRY;WATTAM TREVOR ANTHONY KENNETH |
发明人 |
ASHMAN CLAIRE;CASSIDY MARTIN JOHN;ELLIS JONATHAN HENRY;WATTAM TREVOR ANTHONY KENNETH |
分类号 |
C07K16/24;A61K39/395;A61P1/00;A61P11/06;A61P35/02;A61P37/08;C12N5/10;C12P21/08 |
主分类号 |
C07K16/24 |
代理机构 |
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