发明名称 |
MARKERS FOR DETERMINATION OF PATIENT RESPONSIVENESS |
摘要 |
Compositions and methods are provided for prognostic classification of inflammatory diseases, e.g. inflammatory demyelinating disease, patients into subtypes, which subtypes are informative of the patient's need for therapy and responsiveness to a therapy of interest. The patterns of cytokines provides for a signature pattern that can identify patients likely to benefit from therapeutic intervention as well as discriminate patients that have a high probability of responsiveness to a therapy from those that have a low probability of responsiveness. Assessment of this signature pattern thus allows improved methods of care. In one embodiment of the invention, the autoimmune disease is multiple sclerosis or neuromyelitis optica.
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申请公布号 |
US2011243893(A1) |
申请公布日期 |
2011.10.06 |
申请号 |
US201113026173 |
申请日期 |
2011.02.11 |
申请人 |
AXTELL ROBERT C;STEINMAN LAWRENCE;HAN MAY H;DE JONG BRIGIT A;RAMAN CHANDER;WALKER MICHAEL;SHI JING |
发明人 |
AXTELL ROBERT C.;STEINMAN LAWRENCE;HAN MAY H.;DE JONG BRIGIT A.;RAMAN CHANDER;WALKER MICHAEL;SHI JING |
分类号 |
A61K38/21;A61K31/225;A61K38/02;A61K39/395;A61P25/00;A61P29/00;G06F19/00 |
主分类号 |
A61K38/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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