发明名称 NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
摘要 Heteroaromatic compounds of Formula I: (I) are HIV reverse transcriptase inhibitors, wherein R1, R2, R3; R4 and R5 are defined herein. The compounds of Formula I and their pharmaceutically acceptable salts are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
申请公布号 CA2794377(A1) 申请公布日期 2011.10.06
申请号 CA20112794377 申请日期 2011.03.28
申请人 MERCK CANADA INC. 发明人 BURCH, JASON;COTE, BERNARD;NGUYEN, NATALIE;LI, CHUN SING;ST-ONGE, MIGUEL;GAUVREAU, DANNY
分类号 C07D401/06;A61K31/4439;A61P31/18 主分类号 C07D401/06
代理机构 代理人
主权项
地址