CELL ACTIVITY ANALYZER, METHOD FOR ANALYZING CELL ACTIVITY, AND METHOD FOR IDENTIFYING CELL

摘要

PROBLEM TO BE SOLVED: To analyze the activity of external stimuli to each living cell.SOLUTION: The cell activity analyzer 100 includes: a metal thin film 5 touching living cells C1 and C2; a prism 3 having a boundary surface F touching the metal thin film 5 substantially; a light source 1 emitting a parallel light beam with P polarization incident on the prism 3 with a predetermined angle of incidence to the boundary surface F so as to generate a surface plasmon resonance phenomenon; an objective lens 6 enlarging an image of intensity corresponding to the two-dimensional intensity distribution of the reflected light to a predetermined magnification; an imaging unit 7 for imaging the enlarged intensity image; an image acquisition unit 21 sampling data of the intensity image; a display unit 23 and an operation unit 24 for selecting at least a part of the images of the living cells C1 and C2 as a measured object from the data of the intensity image; and an image processing unit 22 extracting the brightness value of the measured object and calculates the information on the change in intensity of the reflected light of the measured object based on the change in the brightness value of the measured object before and after giving external stimuli to the living cells C1 and C2.