发明名称 COMPOSITION FOR PREDICTING THE RECURRENCE POSSIBILITY AND SURVIVAL PROGNOSIS OF BRAIN TUMOR AND KIT COMPRISING THE SAME
摘要 <p>The present invention relates to a method for using genes on chromosome 17p, MYC/MYCN genes and WNT-related genes as marker genes for predicting the risk of brain tumor recurrence and survival prognosis. More specifically, the present invention relates to a method for predicting the risk of brain tumor recurrence and survival prognosis by completely detecting the deletion of genes on chromosome 17p, the increase in expression of MYC/MYCN genes and no increase in expression of WNT-related genes, and a composition and a kit for predicting the risk of brain tumor recurrence and survival prognosis, using the method. Therefore, the present invention can prevent the recurrence of brain tumors by predicting the recurrence of brain tumors including medulloblastoma in advance, and can be effectively used to increase the survival rate of patients with brain tumor recurrence by predicting the survival prognosis of patients that received treatment for brain tumor.</p>
申请公布号 KR20110110030(A) 申请公布日期 2011.10.06
申请号 KR20110029117 申请日期 2011.03.30
申请人 SNU R&DB FOUNDATION 发明人 PARK, WOONG YANG;PARK, AE KYUNG;KIM, SEUNG KI
分类号 C12Q1/68;C12N15/11;G01N33/574;G01N33/68 主分类号 C12Q1/68
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