Skin permeation device for analyte sensing or transdermal drug delivery

摘要

Devices, systems, kits for increasing the skin's permeability controlled by measured skin electrical parameter are described herein. They may be used for transdermal drug delivery and/or analyte extraction or measurement. The controlled abrasion device contains (i) a hand piece, (ii) an abrasive tip (20), (iii) a feedback control mechanism, (iv) two or more electrodes (42,44), and (v) an electrical motor. Preferably the feedback control mechanism is an internal feedback control mechanism.