发明名称 CGRP RECEPTOR ANTAGONISTS
摘要 Compounds of Formula (I): (wherein variables A1, A2, A3, A4, A5, A6, A7, A8, J, Q, R4, Ea, Eb, Ec, R6, R7, Re, Rf, RPG and Y and Z are as described herein) useful as antagonists of CGRP receptors, and useful in the treatment or prevention of diseases in which CGRP receptors are involved, such as headache, and in particular migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP receptors are involved.
申请公布号 US2011245240(A1) 申请公布日期 2011.10.06
申请号 US200913122769 申请日期 2009.09.30
申请人 STAAS DONNETTE D;BELL IAN M;WOOD MICHAEL R 发明人 STAAS DONNETTE D.;BELL IAN M.;WOOD MICHAEL R.
分类号 A61K31/538;A61K31/437;A61K31/438;A61K31/499;A61P25/00;A61P25/06;C07D471/04;C07D491/107;C07D491/20 主分类号 A61K31/538
代理机构 代理人
主权项
地址