发明名称 PREDICTING RESPONSE TO A HER INHIBITOR
摘要 The present application describes the use of low HER3 as a selection criterion for treating patients with a HER inhibitor, such as pertuzumab. It also describes the use of high HER2:HER3 ratio as a selection criterion for treating cancer patients, such as ovarian cancer patients, with a HER inhibitor, such as pertuzumab. In addition, the application describes the use of high HER3 as a selection criterion for treating cancer patients with a chemotherapeutic agent, for instance gemcitabine.
申请公布号 US2011245103(A1) 申请公布日期 2011.10.06
申请号 US201113151116 申请日期 2011.06.01
申请人 GENENTECH, INC.;HOFFMANN-LA ROCHE. INC. 发明人 AMLER LUKAS C.;BIRKNER MERRILL;LIN CHIN-YU;MOECKS JOACHIM;STRAUSS ANDREAS
分类号 C40B30/04 主分类号 C40B30/04
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