HIGH-THROUGHPUT SENSORIZED BIOREACTOR FOR APPLYING HYDRODYNAMIC PRESSURE AND SHEAR STRESS STIMULI ON CELL CULTURES

摘要

A bioreactor (1) for subjecting a cell culture (3) to a hydrodynamic pressure stimulus is described. This hydrodynamic pressure is generated inside at least one culture chamber (2) by means of variation of the mean distance, with a controlled speed, of a surface relative to the surface on which the culture (3) is positioned and between which the culture medium (5) is free to flow.