发明名称 |
PROCESS FOR THE PRODUCTION OF THE ACTINOBACILLUS PLEUROPNEUMONIAE TOXINS APXI OR APCIII IN A LIQUID CULTURE MEDIUM UNDER SUPPLY OF AIR ENRICHED IN CARBON DIOXIDE |
摘要 |
The current invention pertains to a method to produce RTX-toxins ApxI or ApxIII by culturing Actinobacillus pleuropneumoniae bacteria in a liquid culturing medium that supports growth of the bacteria, characterized in that air is passed through the medium, wherein the air has a carbon dioxide content above normal atmospheric level to increase RTX-toxin production during the production phase of the RTX-toxins. |
申请公布号 |
EP2370591(A1) |
申请公布日期 |
2011.10.05 |
申请号 |
EP20090760847 |
申请日期 |
2009.11.25 |
申请人 |
INTERVET INTERNATIONAL B.V. |
发明人 |
SLAGMAN, SIMEN-JAN;SMITS, CHRISTIAN THEODOOR GERARDUS |
分类号 |
C12P21/02 |
主分类号 |
C12P21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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