| 发明名称 |
PROCESS FOR PRODUCING THE ACTINOBACILLUS PLEUROPNEUMONIAE TOXIN APXI EMPLOYING A CULTURE MEDIUM COMPRISING CALCIUM BOROGLUCONATE |
| 摘要 |
<p>The present invention pertains to a method to produce RTX-toxin Apxl by culturing Actinobacillus pleuropneumoniae bacteria in a liquid culturing medium that supports growth of the bacteria, to which medium a calcium salt is added to form calcium ions in the medium, wherein the culturing medium contains borogluconate to form a calcium borogluconate complex in the medium.</p> |
| 申请公布号 |
EP2370590(A1) |
申请公布日期 |
2011.10.05 |
| 申请号 |
EP20090756520 |
申请日期 |
2009.11.25 |
| 申请人 |
INTERVET INTERNATIONAL B.V. |
发明人 |
SLAGMAN, SIMEN-JAN;SMITS, CHRISTIAN, THEODOOR, GERARDUS;BULUT, BAYRAM |
| 分类号 |
C12P21/02 |
主分类号 |
C12P21/02 |
| 代理机构 |
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