发明名称 Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality
摘要 The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or anα-2-macroglobulin (α2M) preparation with a non-vaccine treatment modality. In particular, an HSP preparation or anα2M preparation is administered in conjunction with a non-vaccine treatment modality for the treatment of cancer or infectious diseases. In the practice of the invention, a preparation comprising HSPs such as but not limited to, hsp70, hsp90 and gp96 alone or in combination with each other, noncovalently or covalently bound to antigenic molecules orα2M, noncovalently or covalently bound to antigenic molecules is administered in conjunction with a non-vaccine treatment modality.
申请公布号 US8029808(B2) 申请公布日期 2011.10.04
申请号 US20090418724 申请日期 2009.04.06
申请人 UNIVERSITY OF CONNECTICUT 发明人 SRIVASTAVA PRAMOD K.
分类号 A61K38/55;A61K39/00;A61K31/4188;A61K31/496;A61K31/7048;A61K38/02;A61K45/06;A61P35/00;A61P35/02 主分类号 A61K38/55
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