发明名称 |
Method for detecting antigen specific or mitogen-activated T cells |
摘要 |
The present invention comprises a method for the quantitative or qualitative detection of antigen-specific CD4+ T cells and/or CD8+ T cells in a subject, said method comprising quantitatively or qualitatively detecting the expression of cell surface marker CD25 and one or more of cell surface markers CD134 and CD137 in a suitable lymphocyte-containing sample from said subject in response to exposure to an antigen. A method for determining the immunocompetence of a subject and a method for isolating antigen-specific CD4+ and/or CD8+ T cells is also disclosed.
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申请公布号 |
US8030005(B2) |
申请公布日期 |
2011.10.04 |
申请号 |
US20070293222 |
申请日期 |
2007.03.20 |
申请人 |
ST. VINCENT'S HOSPITAL SYDNEY LIMITED |
发明人 |
KELLEHER ANTHONY DOMINIC;ZAUNDERS JOHN JAMES |
分类号 |
G01N33/53 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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