发明名称 BIVALENT SMAC MIMETICS AND THE USES THEREOF
摘要 Disclosed is a bivalent mimetic of formula (II) or a compound of formula (XIII) which contains a pyrrolidine ring fused to a 6-8 membered ring where the variables are as defined in the specification. Also disclosed is a pharmaceutical composition comprising a compound of formula (II) or (XIII), a kit comprising a compound of formula (II) or (XIII) and the use of a compound of formula (II) or (XIII) for the manufacture of a pharmaceutical composition for treating a disorder responsive to the induction of apoptosis in an animal or treating hyperproliferative disease.
申请公布号 NZ572531(A) 申请公布日期 2011.09.30
申请号 NZ20070572531 申请日期 2007.05.04
申请人 THE REGENTS OF THE UNIVERSITY OF MICHIGAN 发明人 WANG, SHAOMENG;SUN, HAIYING;QIN, DONGGUANG;NIKOLOVSKA-COLESKA, ZANETA;LU, JIANFENG;QIU, SU;PENG, YUEFENG;CAI, QIAN
分类号 A61K31/00;C07D245/00;C07D245/04;C07D291/00;C07D291/08 主分类号 A61K31/00
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