| 摘要 |
The disclosure relates to a process for preparing PCL-comprising microparticles, to microparticles obtainable by said process, to gel hence obtained and to several uses of the gel such as for the preparation of a medicament for treating a skin abnormality or disfigurement, and/or for controlling bladder function and/or controlling gastric reflux and/or for treating erectile dysfunction and/or for treating vocal cords. The gel may also be used for cosmetic applications. Particularly disclosed is a process for preparing polycaprolactone (PCL)-comprising microparticles, wherein the process comprises the following steps: (a) solubilizing a PCL polymer in a solvent, and mixing the solubilised PCL polymer with a liquid comprising a surfactant, said surfactant being methylcellulose, which is present in a concentration of between about 1 and about 5 w/w%, (b) forming PCL-comprising microparticles from the solution obtained in step (a). |
