发明名称 |
SYNTHESIS OF HDAC INHIBITORS: TRICHOSTATIN A AND ANALOGUES |
摘要 |
Embodiments herein relate to histone deacetylaces (HDACs) and HDAC inhibitors, such as trichostatin A (TSA) and TSA analogues. Embodiments provide simple methods of synthesizing TSA and TSA analogues. These methods provide routes of synthesis of TSA and TSA analogues that enable the production of the HDAC inhibitors at lower cost and in greater quantities than previously were available.
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申请公布号 |
US2011237832(A1) |
申请公布日期 |
2011.09.29 |
申请号 |
US201113028683 |
申请日期 |
2011.02.16 |
申请人 |
UNIVERSITY OF NOTRE DAME DU LAC |
发明人 |
HELQUIST PAUL;SCHAUER DOUGLAS;COSNER CASEY C.;ISKA VIJAYA B.R.;CHATTERJEE ANAMITRA;WIEST OLAF |
分类号 |
C07C259/06 |
主分类号 |
C07C259/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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