发明名称 CROSSLINKED CATION EXCHANGE POLYMERS, COMPOSITIONS AND USE IN TREATING HYPERKALEMIA
摘要 The present invention is directed to crosslinked cation exchange polymers comprising a fluoro group and an acid group, pharmaceutical compositions of these polymers, compositions of a linear polyol and a salt of such polymer. Crosslinked cation exchange polymers having beneficial physical properties, including combinations of particle size, particle shape, particle size distribution, viscosity, yield stress, compressibility, surface morphology, and/or swelling ratio are also described. These polymers and compositions are useful to bind potassium in the gastrointestinal tract.
申请公布号 US2011236340(A1) 申请公布日期 2011.09.29
申请号 US200913060207 申请日期 2009.08.22
申请人 RELYPSA, INC. 发明人 MANSKY PAUL;ALBRECHT DETLEF;BURDICK MICHAEL;CHANG HAN-TING;CHARMOT DOMINIQUE;CONNOR ERIC;HALFON SHERIN;HUANG I-ZU;LIU MINGJUN;CHIDAMBARAM RAMAKRISHNAN;MILLS JONATHAN;STRUEVER WERNER
分类号 A61K31/78;A61P3/02;A61P9/10;A61P13/12 主分类号 A61K31/78
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