REDUCTION OF FLAKE-LIKE AGGREGATION IN NANOPARTICULATE ACTIVE AGENT COMPOSITIONS
摘要
This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions comprising a nanoparticulate active agent, at least one surface stabilizer and a flake-like aggregation reducing agent, such as a buffer and a sugar. The nanoparticulate active agent compositions comprise particles of the active agent having an effective average particle size of less than about 2000 nm.
申请公布号
WO2010138539(A3)
申请公布日期
2011.09.29
申请号
WO2010US36127
申请日期
2010.05.26
申请人
ELAN PHARMA INTERNATIONAL LTD.;RYDE, NIELS, P.;SNYDER, PETER;LIU, WEI;SLIFER, DAVID, M.
发明人
RYDE, NIELS, P.;SNYDER, PETER;LIU, WEI;SLIFER, DAVID, M.