发明名称 COMPOUNDS (CYSTEIN BASED LIPOPEPTIDES) AND COMPOSITIONS AS TLR2 AGONISTS USED FOR TREATING INFECTIONS, INFLAMMATIONS, RESPIRATORY DISEASES ETC.
摘要 The invention provides a novel class of compounds viz. generally lipopeptides like Pam3CSK4, immunogenic compositions and pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors 2. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness a vaccine.
申请公布号 WO2011119759(A1) 申请公布日期 2011.09.29
申请号 WO2011US29661 申请日期 2011.03.23
申请人 IRM LLC;WU, TOM YAO-HSIANG;ZOU, YEFEN;HOFFMAN, TIMOTHY Z.;PAN, JIANFENG 发明人 WU, TOM YAO-HSIANG;ZOU, YEFEN;HOFFMAN, TIMOTHY Z.;PAN, JIANFENG
分类号 A61K31/198;A61K31/17;A61K31/661;A61K38/10;A61P11/00;A61P17/00;A61P29/00;A61P31/00;A61P35/00;C07C323/60;C07K5/04 主分类号 A61K31/198
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