CAPTURE OF MYCOBACTERIA

摘要

Mycobacterium is captured from a sample by treating the sample with a reagent to raise the pH of the sample to at least 10, thereby to provide a high pH sample, and a) contacting said high pH sample with a solid surface such as quaternary ammonium ion exchange beads capable of binding Mycobacteria at the pH of the high pH sample, and separating said surface bearing captured Mycobacteria from said sample or by b) contacting said high pH sample with a capture agent such as pDADMAC capable of binding Mycobacteria at the pH of said high pH sample to form a bound complex of said Mycobacteria and capture agent, and contacting said complex with a solid surface to bind said complex thereto.