发明名称 |
DIRECT DRUG DELIVERY SYSTEM BASED ON THERMALLY RESPONSIVE BIOPOLYMERS |
摘要 |
A method for delivering a drug depot of a compound of interest to a selected region in a subject. The method comprises administering a composition directly to said region of interest, the composition comprising the compound of interest to be delivered (such as an antiinflammatory agent or a chemotherapeutic agent) and a polymer (such as an elastin-like peptide or ELP) that undergoes an inverse temperature phase transition, so that a sustained release of the compound of interest at the selected region is provided. Compositions useful for carrying out the invention are also described.
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申请公布号 |
US2011236384(A1) |
申请公布日期 |
2011.09.29 |
申请号 |
US201113012475 |
申请日期 |
2011.01.24 |
申请人 |
DUKE UNIVERSITY |
发明人 |
SETTON LORI A.;CHILKOTI ASHUTOSH;KRAUS VIRGINIA B.;BETRE HELAWE;DREHER MATTHEW R. |
分类号 |
A61K38/16;A61K39/395;A61P19/02 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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