发明名称 TRICYCLIC INDOLE DERIVATIVES AS PBR LIGANDS
摘要 The present invention provides a PET tracer that has improved properties for imaging the peripheral benzodiazepine receptor (PBR) as compared with known such PET tracers. The present invention also provides a precursor compound useful in the preparation of the PET tracer of the invention and methods for the preparation of said precursor compound and said PET tracer. Also provided by the present invention is a radiopharmaceutical composition comprising the PET tracer of the invention. Methods for using the PET tracer and the radiopharmaceutical composition are also provided.
申请公布号 WO2011117421(A1) 申请公布日期 2011.09.29
申请号 WO2011EP54744 申请日期 2011.03.28
申请人 GE HEALTHCARE LIMITED;ACHANATH, RADHA;BALAJI, SRINATH;FAIRWAY, STEVEN, MICHAEL;MANTZILAS, DIMITRIOS;MOKKAPATI, UMAMAHESHWAR;O'SHEA, DENNIS;PASSMORE, JOANNA, MARIE;SHAN, BO;TRIGG, WILLIAM, JOHN;WADSWORTH, HARRY, JOHN;KADAVILPPARAMPU MOHAMED, AFSAL, MOHAMMED 发明人 ACHANATH, RADHA;BALAJI, SRINATH;FAIRWAY, STEVEN, MICHAEL;MANTZILAS, DIMITRIOS;MOKKAPATI, UMAMAHESHWAR;O'SHEA, DENNIS;PASSMORE, JOANNA, MARIE;SHAN, BO;TRIGG, WILLIAM, JOHN;WADSWORTH, HARRY, JOHN;KADAVILPPARAMPU MOHAMED, AFSAL, MOHAMMED
分类号 C07D209/80;A61K51/04;C07D495/04 主分类号 C07D209/80
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