发明名称 |
DELAYED RELEASE, ORAL DOSAGE COMPOSITIONS THAT CONTAIN AMORPHOUS CDDO-ME |
摘要 |
<p>Pharmaceutical formulations exhibit a desirably low Cmax, among other properties, that contain particles of amorphous bardoxolone methyl, either in pure form or in the form of a solid dispersion, admixed with particles of a hydrophilic binding agent. Such formulations possess the advantage of higher oral bioavailability, relative to formulations based on the crystalline form of bardoxolone methyl.</p> |
申请公布号 |
SG173601(A1) |
申请公布日期 |
2011.09.29 |
申请号 |
SG20110057122 |
申请日期 |
2010.02.12 |
申请人 |
REATA PHARMACEUTICALS, INC. |
发明人 |
ZHANG, JIANG;MEYER, COLIN J. |
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