| 发明名称 |
SUBSTITUTED PROPENYL PIPERAZINE DERIVATIVES AS NOVEL INHIBITORS OF HISTONE DEACETYLASE |
| 摘要 |
This invention comprises the novel compounds of formula (I) wherein R1, R2, R3, R4 and X have defined meanings, having histone deacetylase inhibiting enzymatic activity; their preparation, compositions containing them and their use as a medicine.
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| 申请公布号 |
US2011237585(A1) |
申请公布日期 |
2011.09.29 |
| 申请号 |
US201113048826 |
申请日期 |
2011.03.15 |
| 申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
VAN BRANDT SVEN FRANCISCUS ANNA;VAN EMELEN KRISTOF;ANGIBAUD PATRICK RENE;MARCONNET-DECRANE LAURENCE FRANCOISE BERNADETTE;ARTS JANINE |
| 分类号 |
A61K31/5377;A61K31/496;A61P17/06;A61P35/00;C07D403/04;C07D403/14;C07D413/14 |
主分类号 |
A61K31/5377 |
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