| 摘要 |
Abstract: The present invention provides new processes for the preparation of unsubstituted and substituted 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds which are useful, for example, for preventing or treating diseases or conditions related to an abnormally high level or activity of TNF-a. The invention can provide improved and/or efficient processes for the commercial production of unsubstituted and substituted 4-amino-2-(2,6-dioxopiperidin 3-yl)isoindoline-1,3-dione compounds, including, but not limited to, unsubstituted 4-amino-2 (2,6-dioxopiperidin-3-yl)isoindoline-1,3 -dione. CApoford/SPEC-923391.doc 1.9.11 |
