发明名称 |
TARGETING PAX2 FOR THE INDUCTION OF DEFB1-MEDIATED TUMOR IMMUNITY AND CANCER THERAPY |
摘要 |
Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
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申请公布号 |
US2011236403(A1) |
申请公布日期 |
2011.09.29 |
申请号 |
US201113010867 |
申请日期 |
2011.01.21 |
申请人 |
MEDICAL UNIVERSITY OF SOUTH CAROLINA |
发明人 |
DONALD CARLTON D. |
分类号 |
A61K39/395;A61K31/7088;A61P35/04 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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