The invention provides anti-LRP6 antibodies and methods of using the same. A particular aspect of the invention provides for bispecific anti-LRP6 antibodies that inhibit signaling by multiple Wnt isoforms.
申请公布号
CA2791991(A1)
申请公布日期
2011.09.29
申请号
CA20112791991
申请日期
2011.03.23
申请人
GENENTECH, INC.
发明人
BOURHIS, ERIC;CARANO, RICK;COCHRAN, ANDREA;COSTA, MIKE;DE ALMEIDA, VENITA;ERNST, JAMES;GONG, YAN;HANNOUSH, RAMI;POLAKIS, PAUL;RUBINFELD, BONNEE;SOLLOWAY, MARK;WU, YAN;CAO, TIM CHRISTOPHER