发明名称 |
Use of methylol-containing compounds for the manufacture of a medicament for the treatment of tumors |
摘要 |
<p>The invention provides compounds which contain or are capable of producing a methylol molecule in an aqueous environment, for use in inducing apoptotic death of a neoplastic cell, inhibiting growth of an autologous neoplastic cell in a mammal, inhibiting growth of a drug resistant neoplastic cell in a mammal, killing a neoplastic cell in a mammal, and purging a population of bone marrow cells of neoplastic cells ex vivo.</p> |
申请公布号 |
EP2332542(A3) |
申请公布日期 |
2011.09.28 |
申请号 |
EP20100012266 |
申请日期 |
2000.12.06 |
申请人 |
GEISTLICH PHARMA AG |
发明人 |
CALABRESI, PAUL;DARNOWSKI, JAMES;COSTIN, JAMES |
分类号 |
A61K31/541;C07D233/74;A61K9/06;A61K9/10;A61K9/70;A61K9/72;A61K31/16;A61K31/17;A61K31/18;A61K31/4166;A61K31/505;A61K31/522;A61K31/54;A61K31/549;A61K45/00;A61K45/06;A61P35/00;A61P35/02;A61P35/04;A61P43/00;C07D285/08;C07D285/18 |
主分类号 |
A61K31/541 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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