| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to a method of producing cyclic geminal bis-hydroperoxides from ketones with ring size C12-C15 used to produce 1,2,4,5-tetraoxanes having high anti-parasitic activity. Cyclic geminal bis-hydroperoxides can also be used as radical polymerisation initiators. The disclosed method of producing C12-C15 cyclic geminal bis-hydroperoxides involves reaction of corresponding C12-C15 cycloalkanones with hydrogen peroxide in the presence of boron trifluoride in an ether medium in molar ratio C12-C15 cycloalkanone:boron trifluoride:hydrogen peroxide equal to 1:0.8-1.2:7-12. ^ EFFECT: method enables to obtain C12-C15 cyclic geminal bis-hydroperoxides in a single step and simplifies and lowers the cost of the process, cuts reaction time, as well as labour, material- and power consumption when producing bis-hydroperoxides; method enables to obtain desired products with high output and high selectivity. ^ 1 cl, 1 tbl, 8 ex |
