METHOD OF PREDICTING PREGNANCY IN PROGRAMME OF EXTRACORPORAL FERTILISATION AND TRANSFER OF EMBRYOS IN STANDARD LONG PROTOCOL OF SUPEROVULATION STIMULATION

摘要

FIELD: medicine. ^ SUBSTANCE: before programme of ECF and TE in standard long protocol of superovulation stimulation in patient analysis of hormonal status is performed - content of progesterone receptors in mononuclear fraction of peripheral blood cells is determined. Content of progesterone receptors in mononuclear fraction of peripheral blood cells is determined in the middle of luteal phase of patient's menstrual cycle, before administration of gonadotropin-releasing hormone agonist when carrying out treatment in accordance with standard long protocol of superovulation stimulation. If value is more than 700 progesterone receptors per cell, pregnancy as a result of programme of ECF and TE in standard long protocol of superovulation stimulation is predicted. ^ EFFECT: method ensures analysis simplicity, reduction of its cost, increase of prediction reliability due to taking into account of objective index, indirectly characterising patients' endometrium hormonal status, by determination of progesterone receptors level in mononuclear fraction of peripheral blood cells before beginning treatment. ^ 2 ex