STAT3/5 ACTIVATION INHIBITOR

摘要

An object of the present invention is to provide a STAT3/5 activation inhibitor. The present invention provides a STAT3/5 activation inhibitor containing an aromatic compound represented by the general formula or a salt thereof as an active ingredient: wherein X1 represents a nitrogen atom or a group -CH=, Rrepresents a group -Z-R, in which Z represents a group -CO-, a group -CH(OH)- or the like, Rrepresents a 5-to 15-membered monocyclic, dicyclic or tricyclic saturated or unsaturated heterocyclic group having 1 to 4 nitrogen atoms, oxygen atoms or sulfur atoms, R represents a hydrogen atom or a halogen atom, Rrepresents a group -O-, a group -CO-, a group -CH(OH)-or a lower alkylene group, and A represents a group wherein R represents a hydrogen atom, a lower alkoxy group or the like, p represents 1 or 2, Rrepresents an imidazolyl lower alkyl group or the like.