发明名称 |
CYTOTOXIC AGENTS COMPRISING NEW TOMAYMYCIN DERIVATIVES AND THEIR THERAPEUTIC USE |
摘要 |
<p>The invention relates to novel tomaymicine derivatives comprising a linker. It also relates to the conjugate molecules that comprise one or more of said tomaymicine derivatives covalently linked to a cell binding agent through a linking group that is present on the linker of the tomaymycin derivative. It also relates to the preparation of the tomaymicine derivatives and of the conjugate molecules.</p> |
申请公布号 |
TN2010000002(A1) |
申请公布日期 |
2011.09.26 |
申请号 |
TN20100000002 |
申请日期 |
2010.01.04 |
申请人 |
SANOFI-AVENTIS |
发明人 |
BOUCHARD HERVE;CHARI RAVI V.J.;COMMERCON ALAIN;DENG YONGHONG;GAUZY LAURENCE |
分类号 |
A61K31/5517;A61P35/00;C07D487/04 |
主分类号 |
A61K31/5517 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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