<p>Anti-IL-17 antibodies are identified that are characterized as having a high affinity and slow off rate for human IL-17. The antibodies of the invention may be chimeric, humanized or fully human antibodies, immunoconjugates of the antibodies or antigen- binding fragments thereof. The antibodies of the invention are useful in particular for treating autoimmune, inflammatory, cell proliferative and developmental disorders.</p>
申请公布号
AU2006325860(B2)
申请公布日期
2011.09.22
申请号
AU20060325860
申请日期
2006.12.05
申请人
ELI LILLY AND COMPANY
发明人
NG, KINGMAN;CHOW, CHI-KIN;LIU, LING;ALLAN, BARRETT;LU, JIRONG;TETREAULT, JONATHAN WENDELL;HUANG, LIHUA;WERNER, ANDREW GORDON