| 摘要 |
PROBLEM TO BE SOLVED: To provide a composition that the function of a high-molecular, 2,2,6,6-tetramethyl piperidino oxiradical (TEMPO) is raised, simultaneously such an antioxidant among low-molecular antioxidants excepting TEMPO as is restricted in the applicable field is limited in the effect particularly because of its hardly water-soluble property, is increased in the function. SOLUTION: This composition comprises a low-molecular antioxidant and a high-molecular formed, cyclic nitroxide radical compound. The composition is such that the high-molecular, cyclic nitroxide radical compound has a configuration of a polymer micelle, and the low-molecular antioxidant is included in this polymer micelle. This composition is useful for the medical treatment or prophylaxis of the diseases or disorders in which active oxygen or radical species mediates or participates. COPYRIGHT: (C)2011,JPO&INPIT
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