| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a structure of a novel immunoglobulin heavy chain and an immunoglobulin light chain, which is useful for preparing a transgenic non-human animal expressing a humanized antibody, a recombinant and transgenic vector, a transgenic animal, and a humanized immunoglobulin preparation. <P>SOLUTION: The present invention concerns an isolated nucleic acid molecule comprising a human immunoglobulin gene segment to which a plurality of nucleotide sequences are adjacent. <P>COPYRIGHT: (C)2011,JPO&INPIT |
