发明名称 THERMOSENSITIVE COMPOSITION PREVENTING TISSUE ADHESION AND PREPARATION METHOD THEREOF
摘要 Provided is a thermosensitive composition preventing tissue adhesion and a method for preparing the same, and, more particularly, a thermosensitive composition preventing tissue adhesion which further contains a drug selectively inhibiting inflammatory response and a method for preparing the composition, in which the composition is produced through a chemical reaction by adding a cross-linking agent to an aqueous solution which contains a block copolymer containing a polyethyleneoxide block having the ability to suppress tissue adhesion, and a polymer with 10,000 to 1,000,000 g/mol of molecular weight which can be mixed with the copolymer; the composition is characterized in that the difference of viscosity, absorbance of visible rays region, and stability between the upper and lower liquid layers are within 10% when centrifuging the composition; and also the method for preparing the composition enhances cross-linking homogenization and viscosity stability through simultaneous spraying and stirring methods without a reaction retardant.
申请公布号 US2011229432(A1) 申请公布日期 2011.09.22
申请号 US200913129765 申请日期 2009.09.17
申请人 GENEWEL CO., LTD;HANNAM UNIVERSITY INSTITUTE INDUSTRY-ACADEMIA COOPERATION 发明人 CHOI JIN-SUK;LEE YOUNG-WOO;LEE YUN-GEE;KIM JUN-HO;LEE JIN-HO
分类号 A61K31/765;A61P43/00 主分类号 A61K31/765
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