发明名称 HEPATOCYTE GROWTH FACTOR PATHWAY ACTIVATORS IN DEMYELINATING DISEASES AND CENTRAL NERVOUS SYSTEM TRAUMA
摘要 Methods are provided for treating and preventing demyelinating diseases including multiple sclerosis, and traumatic injury to the central nervous system including brain trauma and spinal cord injury, by administering a compound or pharmaceutical composition of the invention. Useful compounds include hepatocyte growth factor/scatter factor protein, fragments, fusion polypeptides and muteins thereof, and nucleic acid and expression vectors encoding such proteins. Other useful compounds include small molecule HGF/SF agonists and mimetics.
申请公布号 US2011230407(A1) 申请公布日期 2011.09.22
申请号 US201113118317 申请日期 2011.05.27
申请人 YUZHAKOV ALEXANDER 发明人 YUZHAKOV ALEXANDER
分类号 A61K38/22;A61K31/415;A61K31/4155;A61K31/42;A61K31/4439;A61K31/454;A61K31/4704;A61K31/5377;A61K48/00;A61P25/00 主分类号 A61K38/22
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