发明名称 |
METHODS FOR DETECTING DIHYDROXYVITAMIN D METABOLITES BY MASS SPECTROMETRY |
摘要 |
Provided are methods of detecting the presence or amount of a dihydroxyvitamin D metabolite in a sample using mass spectrometry. The methods generally comprise ionizing a dihydroxyvitamin D metabolite in a sample and detecting the amount of the ion to determine the presence or amount of the vitamin D metabolite in the sample. In certain preferred embodiments the methods include immunopurifying the dihydroxyvitamin D metabolites prior to mass spectrometry. Also provided are methods to detect the presence or amount of two or more dihydroxyvitamin D metabolites in a single assay.
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申请公布号 |
US2011226945(A1) |
申请公布日期 |
2011.09.22 |
申请号 |
US201113117997 |
申请日期 |
2011.05.27 |
申请人 |
QUEST DIAGNOSTICS INVESTMENTS INCORPORATED |
发明人 |
HOLMQUIST BRETT;CLARKE NIGEL J.;CASTON-BALDERRAMA ANNE;REITZ RICHARD E. |
分类号 |
H01J49/26 |
主分类号 |
H01J49/26 |
代理机构 |
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地址 |
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