发明名称 |
MATERIALS AND METHODS DIRECTED TO ASPARAGINE SYNTHETASE AND ASPARAGINASE THERAPIES |
摘要 |
Materials and Methods for use in treating cell proliferative disorders related to asparagine metabolism are provided. Cell proliferative disorders include such cancers as forms of leukemia, ovarian cancers, melanomas, renal cancers, breast cancers, brain cancers, and other cancers. Methods include the use of RNA interference targeted at asparagine synthetase to enhance the efficacy of L-asparaginase therapies.
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申请公布号 |
US2011229984(A1) |
申请公布日期 |
2011.09.22 |
申请号 |
US201113151420 |
申请日期 |
2011.06.02 |
申请人 |
THE USA, AS REPRESENTED BY THE SECRETARY, DEP. OFHEALTH AND HUMAN SERVICES |
发明人 |
LORENZI PHILIP L.;WEINSTEIN JOHN N.;CAPLEN NATASHA J. |
分类号 |
G01N33/53;C07K16/40;C12N15/11;C12N15/113 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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地址 |
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