TUMOR ANGIOGENESIS INHIBITOR

摘要

Provided is an antitumor agent, or more specifically, an angiogenesis inhibitor, that contains as an active ingredient a substance which suppresses the expression or function of ENAH. Specifically, the angiogenesis inhibitor contains: an antisense nucleic acid, a ribozyme, or a nucleic acid having RNAi activity for the transcription product of the gene that encodes ENAH; or an antibody, or the like, that binds to ENAH. Also provided is a method for screening angiogenesis inhibitors, characterized in that the genes that encode ENAH, or compounds that reduce the level of expression of ENAH or the function of ENAH, are selected.