发明名称 |
Novel anti-biofilm agents |
摘要 |
Novel agents exhibiting anti-biofilm formation activity while being non-cytotoxic are provided, as well as methods of using the same, either per se or conjugated to a polymer, for preventing and/or reducing the formation of microbial biofilms and/or for disrupting microbial biofilms. The novel agents described herein include thiazolidine-2,4-diones (TZDs), pyrrolidine-2,5-diones (PYDs), imidazolidine-2,4-diones or oxazolidine-2,4-diones, substituted by an alkyl having 7-20 carbon atoms in its backbone chain. |
申请公布号 |
EP2365969(A1) |
申请公布日期 |
2011.09.21 |
申请号 |
EP20090796470 |
申请日期 |
2009.11.19 |
申请人 |
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREWUNIVERSITY OF JERUSALEM;HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENTLTD. |
发明人 |
SREBNIK, Morris;POLACHECK, Itzhack;STEINBERG, Doron;JABBOUR, Adel;SIONOV, Edward |
分类号 |
C07D277/34;A01N43/36;A01N43/78;A61K31/4015;A61K31/426;A61P31/00;C07D207/448;C08F8/14;C08F8/30 |
主分类号 |
C07D277/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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