发明名称 METHOD OF DESTROYING CELLS USING EFFECTOR FUNCTIONS OF ANTI-EphA4 ANTIBODIES
摘要 FIELD: chemistry. ^ SUBSTANCE: disclosed is a method of treating or preventing malignant tumours whose cells express EphA4. The method involves administration of the anti-EphA4 antibody, where the antibody has human IgG1, has VH and VL regions, each containing three corresponding CDR. Described is a pharmaceutical composition based on the antibody for use in the said method. ^ EFFECT: invention can be used in pancreatic cancer therapy. ^ 11 cl, 2 dwg, 1 tbl, 1 ex
申请公布号 RU2429246(C2) 申请公布日期 2011.09.20
申请号 RU20080138541 申请日期 2007.02.22
申请人 ONKOTERAPI SAJENS, INK. 发明人 NAKATSURU SUITI;JOSIKAVA MEGUMI;KHIROSIMA SINITI;KISI JOSIRO;KUKHARA MOTOKI;NISIDA SIJO;SINOKHARA MIDORI
分类号 A61K39/395;A61P35/00;C07K16/28 主分类号 A61K39/395
代理机构 代理人
主权项
地址